With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.29927-08-0,5,6-Dimethylbenzo[d]thiazol-2-amine,as a common compound, the synthetic route is as follows.
General procedure: To the solution of beta-naphthol (1mmol) in methanol were added respective substituted 2-aminobenzothiazole (1mmol) and the synthesized pyrazole aldehyde31 (1mmol). The reaction mixture was refluxed for 5h. The reaction was monitored by TLC and the advantage of this method is that a solid product (white ppt) was formed in the round bottom flask after completion of the reaction. The solid compound was collected by filtration and purified by column chromatography to obtain pure pyrazole linked benzothiazole-beta-naphthol derivatives in good to excellent yields., 29927-08-0
The synthetic route of 29927-08-0 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Nagaraju, Burri; Kovvuri, Jeshma; Kumar, C. Ganesh; Routhu, Sunitha Rani; Shareef, Md. Adil; Kadagathur, Manasa; Adiyala, Praveen Reddy; Alavala, Sateesh; Nagesh, Narayana; Kamal, Ahmed; Bioorganic and Medicinal Chemistry; vol. 27; 5; (2019); p. 708 – 720;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica