79836-78-5,79836-78-5, Ethyl 2-methylthiazole-5-carboxylate is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a 0¡ã C. solution of ethyl 2-methyl-thiazole-5-carboxylate (15 g, 88 mmol) in tetrahydrofuran (50 mL) was added aqueous sodium hydroxide solution (5 N, 50 mL) over 10 minutes, and the resulting solution was stirred at room temperature for another 2 hours. It was then acidified with hydrochloric acid (2 N) to pH=1 and extracted with tetrahydrofuran (3¡Á100 mL). The combined organic layers were washed with brine (30 mL) and dried over sodium sulfate. Most of the solvents were removed under reduced pressure and the residue was lyophilized to afford Compound (E) (14 g).
The synthetic route of 79836-78-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; AMGEN INC.; CHUNG, John Inn; PIRJANIAN, Armen; ALVAREZ-NUNEZ, Fernando Antonio; KATZ, Jeffrey Michael; DAURIO, Dominick Paul; LA, Stevedat; KENNEDY, Michael T.; (52 pag.)US2018/161279; (2018); A1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica