615-21-4,615-21-4, 2-Hydrazinylbenzo[d]thiazole is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
In a four-neck reactor equipped with a thermometer,In a nitrogen stream,10.0 g (60.5 mmol) of 2-hydrazinobenzothiazole was dissolved in 150 ml of DMF.To this solution,39.4 g (121.0 mmol) of cesium carbonate and 9.65 g (72.5 mmol) of 1-bromo-2-butyne were added and the whole of the mixture was stirred at 25 C. for 20 hours.After completion of the reaction, the reaction solution was poured into 1000 ml of water and extracted with 500 ml of ethyl acetate. After drying the ethyl acetate layer with anhydrous sodium sulfate, sodium sulfate was filtered off. Ethyl acetate was distilled off from the filtrate under reduced pressure using a rotary evaporator to obtain a brown solid. This brown solid was purified by silica gel column chromatography (n-hexane: ethyl acetate = 85: 15) to obtain 6.25 g of Intermediate S (yield: 47.5%) as a white solid.
As the paragraph descriping shows that 615-21-4 is playing an increasingly important role.
Reference£º
Patent; ZEON CORPORATION; SAKAMOTO, KEI; OKUYAMA, KUMI; SANUKI, KANAKO; (77 pag.)JP2017/206554; (2017); A;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica