With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.24295-03-2,2-Acetylthiazole,as a common compound, the synthetic route is as follows.
General procedure: To a solution of the appropriate ketone (A, 1 equiv) in chloroform, bromine (1 equiv) in chloroform was added dropwise at 0 C. The mixture was stirred at room temperature for 2 h and was washed with H2O (3 50 ml) and saturated Na2S2O3 solution (2 x 50 ml). The organic phase was dried over Na2SO4, filtered andthe solvent was removed in vacuum. The crude alpha-bromoketone (B) was recrystallized from petrolether.48
24295-03-2, The synthetic route of 24295-03-2 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Vogt, Dominik; Weber, Julia; Ihlefeld, Katja; Brueggerhoff, Astrid; Proschak, Ewgenij; Stark, Holger; Bioorganic and Medicinal Chemistry; vol. 22; 19; (2014); p. 5354 – 5367;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica