32137-76-1, Ethyl 1,3-benzothiazole-2-carboxylate is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Example 6Synthesis of benzothiazole-2-carboxamide (8)Benzothiazole-2-carboxamide was synthesized from ethyl benzothiazole-2-carboxylate according to the following reaction scheme. In particular, commercially available ethyl benzothiazole-2-carboxylate 6 (2.4 mmol, 0.5 g) was dissolved in 34 mL MeOH and purged with NH3 gas. Conversion to the product was monitored by TLC (3 Hexane: 2 EtOAc). Following complete conversion to the product 8 (30 min), the solvent was removed in vacuo. Agilent HPLC displayed 100% conversion to the desired product 8 with a single peak at 8.0 min. The solid white compound was used in the subsequent step without purification. ESI-MS: m/z calcd for C8H6N2OS 179.02 (M+H)+, 179.88 found (100%) (see LC/MS spectra of FIG. 17A and NMR spectra of FIG. 17B)., 32137-76-1
32137-76-1 Ethyl 1,3-benzothiazole-2-carboxylate 640708, athiazole compound, is more and more widely used in various fields.
Reference£º
Patent; GRYSHUK, Amy L.; Perkins, Julie; LaTour, John V.; US2011/224442; (2011); A1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica