With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1603-91-4,4-Methylthiazol-2-amine,as a common compound, the synthetic route is as follows.
To a round bottom flask containing 40 mL CHUCK was added I (695 mg, 6.09 mmol), 4-DMAP (52.3 MG, 0.43 mmol), and BOC20 (1.374 g, 6.29 mmol). The reaction mixture was stirred overnight at room temperature. Concentration of the solution in vacuo was followed by purification by column chromatography (silica gel, hexanes: EtOAc, 10: 1), affording the product as white crystals (54 %)., 1603-91-4
As the paragraph descriping shows that 1603-91-4 is playing an increasingly important role.
Reference£º
Patent; NORTHWESTERN UNIVERSITY; WO2005/26111; (2005); A2;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica