With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1477-42-5,4-Methylbenzo[d]thiazol-2-amine,as a common compound, the synthetic route is as follows.
EXAMPLE 18: 4-METHYL-2-HYDRAZINOBENZOTHIAZOLE To a suspension of 4-methyl-2-aminobenzothiazole (5.0 g., 0.03 mole) in 20 ml. of ethylene glycol was added 5.4 g. of 85% hydrazine hydrate (0.09 mole) and 2.75 g. (0.046 mole) acetic acid. The mixture was heated to 126C. under N2 atmosphere for 3 hours. On cooling and dilution with about 1/2 volume of water the product crystallized.
1477-42-5, As the paragraph descriping shows that 1477-42-5 is playing an increasingly important role.
Reference£º
Patent; Eli Lilly and Company; US3937714; (1976); A;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica