With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.5304-21-2,6-Bromo-2-methylbenzo[d]thiazole,as a common compound, the synthetic route is as follows.,5304-21-2
Compound 11 (114 mg, 0.500 mmol)Was dissolved in methanol (5.00 mL), And benzaldehyde (51.0 muL, 0.500 mmol),Sodium hydroxide (60.0 mg, 1.50 mmol) was added,And heated under reflux for 14 hours under stirring.Precipitated crystals were collected by filtration,And washed with methanol and purified water to obtain Compound 12 in a yield of 50.0 mg (31.8percent).
As the paragraph descriping shows that 5304-21-2 is playing an increasingly important role.
Reference£º
Patent; Kyoto University; Nihon Medi-Physics Co.,Ltd.; Saji, Hideo; Ono, Masahiro; Inohara, Tadashi; Seki, Ikuya; (24 pag.)JP2016/79108; (2016); A;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica