13838-78-3, 5-Methylthiazole-2-carbaldehyde is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Intermediate 3; 2-[[N-(5-Methyl-1 ,3-thiazol-2-yl)methylene]amino]-3-(1 ,3-thiazol-4-yl)propanoic acid, te/1-butyl ester A mixture of 2-amino-3-(1 ,3-thiazol-4-yl)propanoic acid, terf-butyl ester (Intermediate 2; 2.90 g, 12.7 mmol), 5-methyl-1 ,3-thiazole-2-carboxaldehyde (1.62 g, 12.7 mmol) and magnesium sulfate (ca. 1g) in dichloromethane (70 mL) was stirred at room temperature for 18 hours. The reaction mixture was filtered, and the filtrate was evaporated to remove solvent, to give the title compound as an oil.1H NMR (CDCI3): delta 8.75 (d, 1 H), 8.11 (s, 1 H), 7.55(br, 1 H), 7.02 (d, 1 H), 4.45 (dd, 1 H), 3.56 (dd, 1 H), 3.33 (dd, 1 H), 2.50 (br s, 3H) and 1.44 (s, 9H)., 13838-78-3
The synthetic route of 13838-78-3 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; GLAXO GROUP LIMITED; WO2006/45613; (2006); A1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica