With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.61296-22-8,2-Amino-5-bromothiazole monohydrobromide,as a common compound, the synthetic route is as follows.
A mixture of 182 (113 mg, 044 mmoi), Ci (50 mg, 022 mmoi) and cesium carbonate (143 mg, 0.44 mmoi) in MeCN (2 rnL) is stirred at 70 C for 1.5 hours. The mixture is then cooled to room temperature, diluted with DCM (10 niL), washed with water (10 rnL 3), dried over anhydrous sodium sulfate, and concentrated to give crude C25 as a brown solid (80 mg, 56% yield). (MS: [M¡ÂH] 330,1), 61296-22-8
The synthetic route of 61296-22-8 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; IMMUNE SENSOR, LLC; THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM; ZHONG, Boyu; SUN, Lijun; SHI, Heping; LI, Jing; CHEN, Chuo; CHEN, Zhijian; (270 pag.)WO2017/176812; (2017); A1;,
Thiazole | C3H3NS – PubChem
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