With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1826-11-5,2-Phenylthiazole,as a common compound, the synthetic route is as follows.
4.3.1.6 2-Phenylthiazole 11 Following general procedure A, exchange of 2-phenylthiazole 11 (13.8 mg) in the presence of catalyst 1a (4.4 mg) gave [2′,6′-2H2]-11 (12.2 mg, 89%, 82%D). Following general procedure A, exchange of 2-phenylthiazole 11 (13.8 mg) in the presence of catalyst 1b (4.6 mg) gave [2′,6′-2H2]-11 (11.0 mg, 80%, 44%D). Following general procedure A, exchange of 2-phenylthiazole 11 (13.8 mg) in the presence of catalyst 1c (3.8 mg) gave [2′,6′-2H2]-11 (13.6 mg, 98%, 72%D). Following general procedure A, exchange of 2-phenylthiazole 11 (13.8 mg) in the presence of catalyst 5 (3.4 mg) gave [2′,6′-2H2]-11 (10.8 mg, 78%, 59%D). deltaH (300 MHz, DMSO-d6) 7.97-7.93 (m, 3H), 7.78 (d, 1H, J=3.3 Hz), 7.54-7.48 (m, 3H).
1826-11-5, As the paragraph descriping shows that 1826-11-5 is playing an increasingly important role.
Reference£º
Article; Atzrodt, Jens; Derdau, Volker; Kerr, William J.; Reid, Marc; Rojahn, Patrick; Weck, Remo; Tetrahedron; vol. 71; 13; (2015); p. 1924 – 1929;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica