556-90-1, 2-aminothiazol-4(5H)-one is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
556-90-1, General procedure: To the magnetically stirred solution of 17 (232 mg, 2 mmol) in HOAc (7 mL), was added NaOAc (500 mg, 6 mmol). After 15 min 3,4-dimethoxybenzaldhyde (16a, 400 mg, 2.4 mmol) was added and the reaction mixture was heated under reflux for 72 h. The HOAc was removed under reduced pressure and the resultant solid was washed successively with water, methanol and EtOAc to obtain the desired products as solid. 10.2.1.3 5-(4-Hydroxy-3-methoxybenzylidene)-2-iminothiazolidin-4-one (14c) Yellow solid; mp > 200 C; 215 mg, 43% yield; IR (neat) numax = 3364, 2955, 1735, 1680, 1584 cm-1; 1H NMR (400 MHz, CD3SOCD3) delta 9.76 (s, 1H), 9.29 (br s, 1H), 9.05 (s, 1H), 7.50 (s, 1H), 7.13 (s, 1H), 7.06 (d, J = 8.28, 1H), 6.9 (d, J = 7.92, 1H); 13C NMR (100 MHz, CD3SOCD3): delta 175.91, 148.92, 148.35, 130.35, 125.94, 125.81, 123.69, 116.49, 113.88, 56.00; HRMS (ESI-TOF): m/z calculated for C11H10N2O3S [M+H]+, 251.0490; found 251.0491.
556-90-1 2-aminothiazol-4(5H)-one 11175, athiazole compound, is more and more widely used in various fields.
Reference£º
Article; Arfeen, Minhajul; Bhagat, Shweta; Patel, Rahul; Prasad, Shivcharan; Roy, Ipsita; Chakraborti, Asit K.; Bharatam, Prasad V.; European Journal of Medicinal Chemistry; vol. 121; (2016); p. 727 – 736;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica