541-58-2. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 541-58-2, Name is 2,4-Dimethylthiazole
The oxoketene dithioacetals 1 undergo regioselective 1,2-addition with 2-lithiomethyl-4-methylthiazole (2a) and 2-lithiomethylthiazoline (3) to afford the carbinol acetals 4 which on borontrifluoride etherate assisted cyclization yield the corresponding substituted and annelated 3-methyl-5-methylthiothiazolo[3,2-a.] pyridinium tetrafluoroborates (5a-S, 8a, b, 10, 12) and the dihydro derivatives (23-25) respectively in good yields. The corresponding 2-methyl-5-phenylthiazole (16) however underwent both nuclear and side chain deprotonation and yielded a mixture of products under similar reaction conditions.
The oxoketene dithioacetals 1 undergo regioselective 1,2-addition with 2-lithiomethyl-4-methylthiazole (2a) and 2-lithiomethylthiazoline (3) to afford the carbinol acetals 4 which on borontrifluoride etherate assisted cyclization yield the corresponding substituted and annelated 3-methyl-5-methylthiothiazolo[3,2-a.] pyridinium tetrafluoroborates (5a-S, 8a, b, 10, 12) and the dihydro derivatives (23-25) respectively in good yields. The corresponding 2-methyl-5-phenylthiazole (16) however underwent both nuclear and side chain deprotonation and yielded a mixture of products under similar reaction conditions.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. 541-58-2, In my other articles, you can also check out more blogs about 541-58-2
Reference£º
Thiazole | C3H1554NS – PubChem,
Thiazole | chemical compound | Britannica