Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn¡¯t involve a screen. 324579-90-0, C6H8N2S. A document type is Article, introducing its new discovery., Computed Properties of C6H8N2S
Matrix presented. Two six-membered ring targeted analogues of PSMA inhibitors (4a and 4b) were designed on the basis of a computational analysis and synthesized. (E,Z)-Diene 10 was subjected to the nitroso Diels-Alder reaction to give the 1,4-trans six-membered ring adduct, 4a. The cis isomer 4b was derived from similar nitroso cycloaddition reactions with the correspnding (E,E)-diene and separately from cyclohexadiene. The IC50 values of 4a and 4b in a NAALADase assay were found to be 0.9 and 0.1 muM, respectively.
Matrix presented. Two six-membered ring targeted analogues of PSMA inhibitors (4a and 4b) were designed on the basis of a computational analysis and synthesized. (E,Z)-Diene 10 was subjected to the nitroso Diels-Alder reaction to give the 1,4-trans six-membered ring adduct, 4a. The cis isomer 4b was derived from similar nitroso cycloaddition reactions with the correspnding (E,E)-diene and separately from cyclohexadiene. The IC50 values of 4a and 4b in a NAALADase assay were found to be 0.9 and 0.1 muM, respectively.
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Reference£º
Thiazole | C3H5267NS – PubChem,
Thiazole | chemical compound | Britannica