Electric Literature of 2103-99-3, An article , which mentions 2103-99-3, molecular formula is C9H7ClN2S. The compound – 4-(4-Chlorophenyl)thiazol-2-amine played an important role in people’s production and life.
Based on a previously identified lead structure, SC-alphaalphadelta9, we have developed a versatile new chemical scaffold that can be readily modified to generate libraries of both Tyr and dual specificity phosphatase inhibitors with reduced molecular weight and lipophilicity. The most potent analogue identified to date, aminothiazole 8z, inhibits the dual specificity phosphatase Cdc25B with a Ki of 4.6 ¡À 0.4 muM and a Hill coefficient of 2.
Based on a previously identified lead structure, SC-alphaalphadelta9, we have developed a versatile new chemical scaffold that can be readily modified to generate libraries of both Tyr and dual specificity phosphatase inhibitors with reduced molecular weight and lipophilicity. The most potent analogue identified to date, aminothiazole 8z, inhibits the dual specificity phosphatase Cdc25B with a Ki of 4.6 ¡À 0.4 muM and a Hill coefficient of 2.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 2103-99-3, help many people in the next few years., Electric Literature of 2103-99-3
Reference£º
Thiazole | C3H10233NS – PubChem,
Thiazole | chemical compound | Britannica