A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 656-53-1, Name is 2-(4-Methylthiazol-5-yl)ethyl acetate, molecular formula is C8H11NO2S. In a Article£¬once mentioned of 656-53-1, Computed Properties of C8H11NO2S
Bridged thiazolium salts 16b and c have been synthesized in a short procedure starting with omega-amino acids.Condensation with carbon disulfide and alpha-chloro ketone 19 provided thiazole-2(3H)-thiones 14b and c and the bridge was then formed by standard macrolactonization procedures.Oxidation of the thiones with hydrogen peroxide then gave the thiazolium salts.The same cyclization procedures failed to yield the shorter bridged compound 15a but gave the cyclic dimer and trimer.Starting with protected lysine derivatives 31b and c, thiazole-2(3H)-thiones 36b and c were obtained.In both cases the cyclization reaction yielded two separable atropisomers depending on which side of the ring the bridge was formed.The catalytic reactions of thiazolium salts 16b and c were compared with unbridged analogues and it was found that, whereas the longer bridged one behaved normally, the shorter bridged salt was unable to catalyse the benzoin condensation.A novel 2-benzoyl-2,3-dihydrothiazole 44 was isolated from this reaction mixture.
Bridged thiazolium salts 16b and c have been synthesized in a short procedure starting with omega-amino acids.Condensation with carbon disulfide and alpha-chloro ketone 19 provided thiazole-2(3H)-thiones 14b and c and the bridge was then formed by standard macrolactonization procedures.Oxidation of the thiones with hydrogen peroxide then gave the thiazolium salts.The same cyclization procedures failed to yield the shorter bridged compound 15a but gave the cyclic dimer and trimer.Starting with protected lysine derivatives 31b and c, thiazole-2(3H)-thiones 36b and c were obtained.In both cases the cyclization reaction yielded two separable atropisomers depending on which side of the ring the bridge was formed.The catalytic reactions of thiazolium salts 16b and c were compared with unbridged analogues and it was found that, whereas the longer bridged one behaved normally, the shorter bridged salt was unable to catalyse the benzoin condensation.A novel 2-benzoyl-2,3-dihydrothiazole 44 was isolated from this reaction mixture.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Computed Properties of C8H11NO2S. In my other articles, you can also check out more blogs about 656-53-1
Reference£º
Thiazole | C3H929NS – PubChem,
Thiazole | chemical compound | Britannica