In an article, published in an article, once mentioned the application of 1603-91-4, Name is 4-Methylthiazol-2-amine,molecular formula is C4H6N2S, is a conventional compound. this article was the specific content is as follows.Recommanded Product: 4-Methylthiazol-2-amine
An effective and economical preparation of bis-(2-thiazolyl)amine analogues was achieved by the reaction of 3-(5-arylazothiazol-2-yl)thioureas with various halogenated carbonyl reagents (namely; chloroacetic acid, diethyl bromomalonate, chloroacetone and phenacyl bromide). The physical and spectral analyses were performed to demonstrate the correct configurations of all incorporated analogues. It is clear that most of synthesized bis-(2-thiazolyl)amine derivatives revealed good biological efficacy, including anticancer, antibacterial and antioxidant. The synthesized bis-(2-thiazolyl)amine derivatives were investigated as cytotoxic agents against four different cell lines, in which the results revealed potent efficacies of the synthesized derivatives relative to the results of antibiotic standards. In addition, the antioxidant efficacy of all analogues was determined using ABTS?+ ?2,2?-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid? method.
An effective and economical preparation of bis-(2-thiazolyl)amine analogues was achieved by the reaction of 3-(5-arylazothiazol-2-yl)thioureas with various halogenated carbonyl reagents (namely; chloroacetic acid, diethyl bromomalonate, chloroacetone and phenacyl bromide). The physical and spectral analyses were performed to demonstrate the correct configurations of all incorporated analogues. It is clear that most of synthesized bis-(2-thiazolyl)amine derivatives revealed good biological efficacy, including anticancer, antibacterial and antioxidant. The synthesized bis-(2-thiazolyl)amine derivatives were investigated as cytotoxic agents against four different cell lines, in which the results revealed potent efficacies of the synthesized derivatives relative to the results of antibiotic standards. In addition, the antioxidant efficacy of all analogues was determined using ABTS?+ ?2,2?-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid? method.
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Reference£º
Thiazole | C3H9862NS – PubChem,
Thiazole | chemical compound | Britannica