73040-66-1, Name is 5-(4-Chlorophenyl)thiazol-2-amine, molecular formula is C9H7ClN2S, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 73040-66-1, COA of Formula: C9H7ClN2S
The synthesis and biological evaluation of a variety of 4-(heteroarylaminomethyl)-N-(2-aminophenyl)-benzamides and their analogs is described. Some of these compounds were shown to inhibit HDAC1 with IC50 values below the micromolar range, induce hyperacetylation of histones, upregulate expression of the tumor suppressor p21WAF1/Cip1, and inhibit proliferation of human cancer cells. In addition, certain compounds of this class were active in several human tumor xenograft models in vivo.
The synthesis and biological evaluation of a variety of 4-(heteroarylaminomethyl)-N-(2-aminophenyl)-benzamides and their analogs is described. Some of these compounds were shown to inhibit HDAC1 with IC50 values below the micromolar range, induce hyperacetylation of histones, upregulate expression of the tumor suppressor p21WAF1/Cip1, and inhibit proliferation of human cancer cells. In addition, certain compounds of this class were active in several human tumor xenograft models in vivo.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.COA of Formula: C9H7ClN2S. In my other articles, you can also check out more blogs about 73040-66-1
Reference£º
Thiazole | C3H5964NS – PubChem,
Thiazole | chemical compound | Britannica