The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.53137-27-2, Name is 2,4-Dimethylthiazole-5-carboxylic acid, molecular formula is C6H7NO2S. In a Patent£¬once mentioned of 53137-27-2, Recommanded Product: 53137-27-2
A compound of formula (1), wherein:R 5 is hydrogen, C 1-4 alkyl, R 6 CH 2 ? or R 6 C(O)?; R 6 is aryl, heteroaryl, heterocyclyl, aminoC 3-6 alkyl, N-(C 1-4 alkyl)aminoC 3-6 alkyl, NN-(diC 1-4 alkyl)aminoC 3-6 alkyl, or R 7 ; wherein the aryl, heteroaryl or heterocyclyl rings may be optionally substituted with up to three substituents independently selected from nitro, C 1-4 alkyl, C 1-4 alkoxy, halo, (C 1-4 alkyl)sulfanyl, C 1-4 alkoxycarbonyl, N-(C 1-4 alkyl)carbamoyl, NN-(diC 1-4 alkyl)carbamoyl, N-(C 1-4 alkyl)amino or NN-(diC 1-4 alkyl)amino; wherein R 7 is either a group or formula (2) or formula (3); and wherein L 1 , L 2 , L 3 , L 4 , R 1 , R 2 , R 3 , R 4 , R 8 , R 9 , R 10 , R 11 , R 12 , R 13 , A 1 , n, p, q, r and s are as defined herein. The compounds of formula (1) inhibit the interactions between MDM2 and p53 and may be useful in the treatment of cancers
A compound of formula (1), wherein:R 5 is hydrogen, C 1-4 alkyl, R 6 CH 2 ? or R 6 C(O)?; R 6 is aryl, heteroaryl, heterocyclyl, aminoC 3-6 alkyl, N-(C 1-4 alkyl)aminoC 3-6 alkyl, NN-(diC 1-4 alkyl)aminoC 3-6 alkyl, or R 7 ; wherein the aryl, heteroaryl or heterocyclyl rings may be optionally substituted with up to three substituents independently selected from nitro, C 1-4 alkyl, C 1-4 alkoxy, halo, (C 1-4 alkyl)sulfanyl, C 1-4 alkoxycarbonyl, N-(C 1-4 alkyl)carbamoyl, NN-(diC 1-4 alkyl)carbamoyl, N-(C 1-4 alkyl)amino or NN-(diC 1-4 alkyl)amino; wherein R 7 is either a group or formula (2) or formula (3); and wherein L 1 , L 2 , L 3 , L 4 , R 1 , R 2 , R 3 , R 4 , R 8 , R 9 , R 10 , R 11 , R 12 , R 13 , A 1 , n, p, q, r and s are as defined herein. The compounds of formula (1) inhibit the interactions between MDM2 and p53 and may be useful in the treatment of cancers
The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 53137-27-2 is helpful to your research., Recommanded Product: 53137-27-2
Reference£º
Thiazole | C3H1694NS – PubChem,
Thiazole | chemical compound | Britannica