Electric Literature of 188672-83-5, Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology.188672-83-5, Name is 6-Nitrobenzo[d]thiazole-2-carbonitrile, molecular formula is C8H3N3O2S. In a patent, introducing its new discovery.
Bioluminescence imaging with luciferase-luciferin pairs is a popular method for visualizing biological processes in vivo. Unfortunately, most luciferins are difficult to access and remain prohibitively expensive for some imaging applications. Here we report cost-effective and efficient syntheses of d-luciferin and 6?-aminoluciferin, two widely used bioluminescent substrates. Our approach employs inexpensive anilines and Appel’s salt to generate the luciferin cores in a single pot. Additionally, the syntheses are scalable and can provide multi-gram quantities of both substrates. The streamlined production and improved accessibility of luciferin reagents will bolster in vivo imaging efforts. This journal is
Bioluminescence imaging with luciferase-luciferin pairs is a popular method for visualizing biological processes in vivo. Unfortunately, most luciferins are difficult to access and remain prohibitively expensive for some imaging applications. Here we report cost-effective and efficient syntheses of d-luciferin and 6?-aminoluciferin, two widely used bioluminescent substrates. Our approach employs inexpensive anilines and Appel’s salt to generate the luciferin cores in a single pot. Additionally, the syntheses are scalable and can provide multi-gram quantities of both substrates. The streamlined production and improved accessibility of luciferin reagents will bolster in vivo imaging efforts. This journal is
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Reference£º
Thiazole | C3H7402NS – PubChem,
Thiazole | chemical compound | Britannica