A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 64359-81-5, Name is 4,5-Dichloro-2-octylisothiazol-3(2H)-one, molecular formula is C11H17Cl2NOS. In an article, author is Xi, Hui,once mentioned of 64359-81-5, Formula: C11H17Cl2NOS.
G-quadruplex based biosensor: A potential tool for SARS-CoV-2 detection
G-quadruplex is a non-canonical nucleic acid structure formed by the folding of guanine rich DNA or RNA. The conformation and function of G-quadruplex are determined by a number of factors, including the number and polarity of nucleotide strands, the type of cations and the binding targets. Recent studies led to the discovery of additional advantageous attributes of G-quadruplex with the potential to be used in novel biosensors, such as improved ligand binding and unique folding properties. G-quadruplex based biosensor can detect various substances, such as metal ions, organic macromolecules, proteins and nucleic acids with improved affinity and specificity compared to standard biosensors. The recently developed G-quadruplex based biosensors include electrochemical and optical biosensors. A novel G-quadruplex based biosensors also show better performance and broader applications in the detection of a wide spectrum of pathogens, including SARS-CoV-2, the causative agent of COVID-19 disease. This review highlights the latest developments in the field of G-quadruplex based biosensors, with particular focus on the G-quadruplex sequences and recent applications and the potential of Gquadruplex based biosensors in SARS-CoV-2 detection.
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Reference:
Thiazole | C3H3NS – PubChem,
,Thiazole | chemical compound | Britannica