Chemistry, like all the natural sciences, Computed Properties of C8H12N2O2S, begins with the direct observation of nature¡ª in this case, of matter.1235406-42-4, Name is tert-Butyl thiazol-4-ylcarbamate, SMILES is O=C(OC(C)(C)C)NC1=CSC=N1, belongs to thiazoles compound. In a document, author is Shaaban, Mohamed R., introduce the new discover.
Synthesis, Antimicrobial and Anticancer Evaluations of Novel Thiazoles Incorporated Diphenyl Sulfone Moiety
A novel series of thiazoles incorporated phenylsulfonyl group have been designed and synthesized from the treatment of N-(1-(4-(phenylsulfonyl)phenyl)ethylidene)hydrazine carbothioamide with various types of alpha-halocarbonyl compounds in one-pot reaction strategy under microwaves irradiations. Studying all possible spectral data for the prepared compounds were proved their structure as well as the suggested mechanism of their reactions. The results of antimicrobial activity of some selected derivatives proved their potency in which some derivatives showed activity exceeded the activity of the reference drugs. In addition, selected derivatives were investigated for their anticancer activities against HepG-2 and HCT-116 cell lines to shed some light on the anticancer activity of the newly synthesized thiazole derivatives. One of the tested thiazole derivatives showed good activity in comparison with doxorubicin reference.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 1235406-42-4. Computed Properties of C8H12N2O2S.
Reference:
Thiazole | C3H3NS – PubChem,
,Thiazole | chemical compound | Britannica