Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels. 121-66-4, Name is 5-Nitrothiazol-2-amine, molecular formula is C3H3N3O2S. In an article, author is Sanad, Sherif M. H.,once mentioned of 121-66-4, Product Details of 121-66-4.
Efficient synthesis and characterization of novel bis(chromenes) and bis(benzo[f]chromenes) linked to thiazole units
New carbothioamides, linked to chromene or benzo[f]chromene units, were taken as key synthons for the present study. These carbothioamides were prepared, in good yields, by the cyclocondensation of the appropriate 2-hydroxybenzaldehydes or 2-hydroxy-1-naphthaldehyde with 2-cyanoethanethioamide. Next, the precursors carbothioamides were reacted with different alpha-halocarbonyl compounds and bis(alpha-bromoketones). These reactions afforded the corresponding 4-(substituted)thiazoles and thiazol-4(5H)-ones, in addition to bis(thiazoles), linked to different cores. Additionally, thiazol-4(5H)-ones were condensed with the appropriate bis(aldehydes) to yield the corresponding bis(thiazol-4(5H)-ones), linked to chromene or benzo[f]chromene units via different cores.
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Reference:
Thiazole | C3H3NS – PubChem,
,Thiazole | chemical compound | Britannica