Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, Product Details of 55981-09-455981-09-4, Name is 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate, SMILES is CC(OC1=CC=CC=C1C(NC2=NC=C([N+]([O-])=O)S2)=O)=O, belongs to thiazoles compound. In a article, author is Hui, Yonghai, introduce new discover of the category.
Facile synthesis of spiro thiazolidinone via cyclic ketones, amines and thioglycolic acid by MCM-41-Schiff base-CuSO4 center dot 5H(2)O
Mesoporous MCM-41-supported Schiff base and CuSO(4)Greek ano teleia5H(2)O (MCM-41@Schiff base-CuSO(4)Greek ano teleia5H(2)O) catalyzed one-pot three-component condensation of cyclic ketones, amines and thioglycolic acid in toluene. And a series of corresponding spiro thiazolidinone derivatives were obtained in high yields (up to 97%). The synthesized catalyst was characterized via FT-IR, XRD, SEM, TEM and EDS and can be easily recovered by centrifugation and reused at 10 times without any change in catalytic activity. Moreover, the scale-up experiment also demonstrated the practicability of the catalytic system on the condensation. The possible mechanisms pave the way to investigation on the reactions of other cyclic ketones with thioglycolic acid.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 55981-09-4. Product Details of 55981-09-4.
Reference:
Thiazole | C3H3NS – PubChem,
,Thiazole | chemical compound | Britannica