Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Bondock, Samir, once mentioned the application of 55981-09-4, Name is 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate, molecular formula is C12H9N3O5S, molecular weight is 307.282, MDL number is MFCD00416599, category is thiazoles. Now introduce a scientific discovery about this category, COA of Formula: C12H9N3O5S.
Advances in the synthesis and chemical transformations of 5-acetyl-1,3,4-thiadiazolines
5-Acetyl-1,3,4-thiadiazolines are a versatile class of heterocycles which find wide application in medicinal and materials chemistry. The objective of this review is to describe the different strategies developed so far for the synthesis of 5-acetyl-1,3,4-thiadiazolines and their analogues as well as to highlight their reactivity in the synthesis of chemically relevant bioactive heterocyclic compounds. The first part of this review describes the diverse synthetic approaches to synthesize 5-acetyl-1,3,4-thiadiazolines based on the [4 pi + 2 pi] cycloaddition reaction of C-acetyl nitrile imines with reagents having sulfur diploarphiles. The synthetic methods have been organized on the basis of the type of sulfur reagent employed in the syntheses. In the second part, an overview of the transformations of 5-acetyl-1,3,4-thiazolines into heterocyclic compounds such as pyrazoles, thiazoles, 1,3,4-thiadiazoles, imidazoles, pyridines, and pyrimidines as well as other relevant condensed derivatives, is presented.
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Reference:
Thiazole | C3H3NS – PubChem,
,Thiazole | chemical compound | Britannica