Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 181124-40-3, Name is Benzo[d]thiazole-6-sulfonyl chloride, molecular formula is C7H4ClNO2S2, belongs to thiazoles compound, is a common compound. In a patnet, author is Kasare, Sanghratna L., once mentioned the new application about 181124-40-3, Computed Properties of C7H4ClNO2S2.
Synthesis, antimicrobial screening, and docking study of new 2-(2-ethylpyridin-4-yl)-4-methyl-N-phenylthiazole-5-carboxamide derivatives
A series of new 2-(2-ethylpyridin-4-yl)-4-methyl-N-phenylthiazole-5-carboxamide derivatives (5a-l) were synthesized and evaluated for their in vitro antimicrobial activities. Among the screened compounds,5b,5d,5e,5f,and5jhave shown promising antimicrobial activities against both bacterial and fungal pathogens. A molecular docking study was conducted to know the probable mode of action of synthesized derivatives for antimicrobial activity. The active compounds have shown excellent binding affinity towardDNA gyraseandlumazine synthaseenzymes. The physicochemical properties of the synthesized thiazole-carboxamide derivatives were calculated. It has displayed the potential to be a reasonable oral bioavailability drug as determined by Lipinski’s rule.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 181124-40-3. The above is the message from the blog manager. Computed Properties of C7H4ClNO2S2.
Reference:
Thiazole | C3H3NS – PubChem,
,Thiazole | chemical compound | Britannica