Archives for Chemistry Experiments of 121-66-4

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Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Kotha, Sambasivarao, once mentioned the application of 121-66-4, Name is 5-Nitrothiazol-2-amine, molecular formula is C3H3N3O2S, molecular weight is 145.14, MDL number is MFCD00005326, category is thiazoles. Now introduce a scientific discovery about this category, Computed Properties of C3H3N3O2S.

DESIGN AND SYNTHESIS OF PENTACYCLOUNDECANE CAGE COMPOUND CONTAINING OXAZOLE MOIETY

Here, we have established a new and simple synthetic approach to the pentacycloundecane containing cage oxazole unit in four steps. The synthesis begun with a cheap and readily available materials such as 2,5-dimethoxybenzaldehyde and endo-dicyclopentadiene. This approach relies on Van Leusen oxazole synthesis and [2+2] photocycloaddition as key steps. To the best of our knowledge, this is the first example of Cookson’s dione containing oxazole ring system. Some of these oxazole motifs are useful in bioorganic chemistry and our results are likely to draw the attention of medicinal chemists

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Reference:
Thiazole | C3H3NS – PubChem,
,Thiazole | chemical compound | Britannica