Reference of 35272-15-2, Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology.35272-15-2, Name is 2-Methylthiazole-4-carboxylic acid, molecular formula is C5H5NO2S. In a patent, introducing its new discovery.
Molecular design and chemical synthesis of several palmerolide A analogues allowed the first structure activity relationships (SARs) of this newly discovered marine antitumor agent. From several analogues synthesized and tested (ent-1, 5-14, 21-26, 50, 51), compounds 25 (with a phenyl substituent on the side chain) and 51 (lacking the C-7 hydroxyl group) were the most interesting, exhibiting approximately a 10-fold increase in potency and equipotency, respectively, to the natural product. These findings point the way to more focused structure activity relationship studies.
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Reference£º
Thiazole | C3H3847NS – PubChem,
Thiazole | chemical compound | Britannica