3581-87-1, Name is 2-Methylthiazole, molecular formula is C4H5NS, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 3581-87-1, Formula: C4H5NS
Known and novel histaminergic H1- and H2-receptor agonists were investigated as potentially potent and selective brain-penetrating compounds. Structural modifications were introduced in an attempt to favour passive diffusion across the blood-brain injury by reducing hydrogen-bonding ability according to a previously developed model. While no novel compound was identified which satisfied our requirements for a brain-penetrating agonist, betahistine 14 and 2-(thiazol-2-yl)ethylamine 16 can be regarded as H1-receptor agonists with moderate brain-penetrating ability, of potential value as pharmacological tools. A novel histamine analogue, N,N-bis-{2-[4(5)-imidazolyl]ethyl}amine 25 is reported which, although unlikely to be brain penetrant, was found to be equipotent with histamine at H1- and H1-receptors.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Formula: C4H5NS. In my other articles, you can also check out more blogs about 3581-87-1
Reference£º
Thiazole | C3H3720NS – PubChem,
Thiazole | chemical compound | Britannica