A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 20485-41-0, Name is 4-Methylthiazole-5-carboxylic acid, molecular formula is C5H5NO2S. In a Patent£¬once mentioned of 20485-41-0, Application In Synthesis of 4-Methylthiazole-5-carboxylic acid
The invention relates to a heterocyclic carboxylic acid compound decarboxylate the method, the heterocyclic carboxylic acid compound is soluble in the non-proton hydroxylated solvent N, N – dimethyl formamide, in the 85 C -150 C, organic acid as catalyst under the condition of decarboxylation. The invention compared with the prior art in the decarboxylation method, reaction to obtain the decarboxylation product yield is higher, and does not require the use of expensive metal catalyst; at the same time, compared with the DMSO, in the invention of the solvent (DMF) is more stable, difficult to decompose under the high temperature, also can be recycled, and the cost is reduced. The operation of the invention process is simple, zero pollution, environmental protection, it has very good application prospect. (by machine translation)
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.Application In Synthesis of 4-Methylthiazole-5-carboxylic acid, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 20485-41-0, in my other articles.
Reference£º
Thiazole | C3H5821NS – PubChem,
Thiazole | chemical compound | Britannica