Archives for Chemistry Experiments of 29198-43-4

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Synthetic Route of 29198-43-4. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 29198-43-4, Name is 2-Benzothiazolecarboxamide

Design, synthesis and biological activity evaluation of novel 2,6-difluorobenzamide derivatives through FtsZ inhibition

Novel series of 3-substituted 2,6-difluorobenzamide derivatives as FtsZ inhibitors were designed, synthesized and evaluated for their in vitro antibacterial activity against various phenotype of Gram-positive and Gram-negative bacteria, and their cell division inhibitory activity against three representative strains. As a result, 3-chloroalkoxy derivative 7, 3-bromoalkoxy derivative 12 and 3-alkyloxy derivative 17 were found to exhibit the best antibacterial activity against Bacillus subtilis with MICs of 0.25?1 mug/mL, and good activity (MIC < 10 mug/mL) against both susceptible and resistant Staphylococcus aureus. Additionally, all the three compounds displayed potent cell division inhibitory activity with MIC values of below 1 mug/mL against Bacillus subtilis and Staphylococcus aureus. If you are hungry for even more, make sure to check my other article about 29198-43-4. Synthetic Route of 29198-43-4

Reference:
Thiazole | C3H2336NS – PubChem,
Thiazole | chemical compound | Britannica