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5-fluoro -2,4- pyrimidine diamine compound as well as preparation method and application thereof (by machine translation)

The invention provides a (I) fluorine – 2222, pyrimidine diamine compound 5 – with the structure, as well as a preparation method and application, of the antitumor drug in preparation of antitumor drugs, for treating liver cancer, lung cancer or leukemia provided by the invention has a remarkable inhibition effect (I) to, cell strains; cell strains of the cell strain HepG – 2 of the cell strain . A549. The invention provides a preparation method, HL – 60 of the antitumor activity; serving as a new drug screening in preparation of, anti-tumor drugs, and the preparation, method is simple, conducive, to industrial production (I). (by machine translation)

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Reference:
Thiazole | C3H4809NS – PubChem,
Thiazole | chemical compound | Britannica