A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 5331-91-9, Name is 5-Chlorobenzo[d]thiazole-2(3H)-thione, molecular formula is C7H4ClNS2. In a Article，once mentioned of 5331-91-9, category: thiazole
Synthesis, in vitro alpha-glucosidase inhibitory activity and molecular docking studies of novel benzothiazole-triazole derivatives
Benzothiazole-triazole derivatives 6a?6s have been synthesized and characterized by1H-NMR and13C-NMR. All synthetic compounds were screened for their in vitro alpha-glucosidase inhibitory activity by using Baker?s yeast alpha-glucosidase enzyme. The majority of compounds exhibited a varying degree of alpha-glucosidase inhibitory activity with IC50 values between 20.7 and 61.1 muM when compared with standard acarbose (IC50 = 817.38 muM). Among the series, compound 6s (IC50 = 20.7 muM) bearing a chlorine group at the 5-position of the benzothiazole ring and a tert-butyl group at the para position of the phenyl ring, was found to be the most active compound. Preliminary structure-activity relationships were established. Molecular docking studies were performed to predict the binding interaction of the compounds in the binding pocket of the enzyme.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.category: thiazole, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 5331-91-9, in my other articles.
Reference：
Thiazole | C3H6348NS – PubChem,
Thiazole | chemical compound | Britannica