A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 1849-65-6, Name is 4-Chlorobenzo[d]thiazole-2-thiol, molecular formula is C7H4ClNS2. In a Article，once mentioned of 1849-65-6, Recommanded Product: 1849-65-6
We report on the discovery of benzo- and pyridinothiazolothiopurines as potent heat shock protein 90 inhibitors. The benzothiazole moiety is exceptionally sensitive to substitutions on the aromatic ring with a 7?-substituent essential for activity. Some of these compounds exhibit low nanomolar inhibition activity in a Her-2 degradation assay (28-150 nM), good aqueous solubility, and oral bioavailability profiles in mice. In vivo efficacy experiments demonstrate that compounds of this class inhibit tumor growth in an N87 human colon cancer xenograft model via oral administration as shown with compound 37 (8-(7-chloro-benzothiazol-2-ylsulfanyl)-9-(2-cyclopropylamino-ethyl) -9H-purin-6-ylamine).
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.Recommanded Product: 1849-65-6, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 1849-65-6, in my other articles.
Reference：
Thiazole | C3H5243NS – PubChem,
Thiazole | chemical compound | Britannica