The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.566169-93-5, Name is 2-(4-(Methylamino)phenyl)benzo[d]thiazol-6-ol, molecular formula is C14H12N2OS. In a Article,once mentioned of 566169-93-5, Application In Synthesis of 2-(4-(Methylamino)phenyl)benzo[d]thiazol-6-ol
Three novel 99mTc-labeled pyridyl benzofuran derivatives were tested as potential probes for imaging beta-amyloid plaques using single photon emission computed tomography (SPECT). The 99mTc and corresponding rhenium complexes were synthesized with bis(aminoethanethiol) (BAT) as a chelating ligand. All Re complexes showed affinity for Abeta(1-42) aggregates (Ki = 13.6-149.6 nM). Biodistribution experiments in normal mice revealed that the 99mTc-labeled derivatives displayed sufficient uptake in the brain (1.41-1.80% ID/g at 2 min postinjection). Notably, [99mTc]BAT-Bp-2 showed a good initial uptake (1.80% ID/g at 2 min) and a reasonable washout from the brain (0.79% ID/g at 60 min). Ex vivo autoradiography with [99mTc]BAT-Bp-2 revealed substantial labeling of beta-amyloid plaques in sections of brain tissue from Tg2576 transgenic mice but not in the age-matched controls. [99mTc]BAT-Bp-2 may be a potential SPECT probe for imaging beta-amyloid plaques in Alzheimer’s brains.
The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 566169-93-5 is helpful to your research., Application In Synthesis of 2-(4-(Methylamino)phenyl)benzo[d]thiazol-6-ol
Reference:
Thiazole | C3H423NS – PubChem,
Thiazole | chemical compound | Britannica