Reference of 40283-46-3. Let’s face it, organic chemistry can seem difficult to learn. Especially from a beginner’s point of view. Like 40283-46-3, Name is 2-Aminothiazole-5-carboxylic acid. In a document type is Article, introducing its new discovery.
The rate constants of the decarboxylation reaction of 2-amino- and 2-phenylamino-thiazole-5-carboxylic acid (3a-b), and, for comparison, of 5-phenylamino-1,3,4-thiadiazole-2-carboxylic acid (2b) have been measured in water over a range of proton activities.The results obtained suggest: (i) compound 2b decarboxylates, in the whole range of proton activity studied, through a unimolecular decarboxyprotonation mechanism characteristic of 1,3,4-oxa- and 1,3,4-thiadiazole derivatives; (ii) in contrast, 3a-b decarboxylate via either a unimolecular decarboxyprotonation or a bimolecular protiodecarboxylation mechanism as a function of proton activity.
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Reference：
Thiazole | C3H2321NS – PubChem,
Thiazole | chemical compound | Britannica