Month: June 2021

21303-50-4, Name is 5-Methylbenzo[d]thiazole-2-thiol, molecular formula is C8H7NS2, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 21303-50-4, Quality Control of: 5-Methylbenzo[d]thiazole-2-thiol

A selective herbicidal composition comprising an effective amount of a compound of the formula SPC1 Wherein R is selected from the group consisting of isopropyl and tertbutyl.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Quality Control of: 5-Methylbenzo[d]thiazole-2-thiol. In my other articles, you can also check out more blogs about 21303-50-4

Reference：
Thiazole | C3H6485NS – PubChem,
Thiazole | chemical compound | Britannica

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 121-66-4, Name is 5-Nitrothiazol-2-amine, molecular formula is C3H3N3O2S. In a Patent，once mentioned of 121-66-4, Quality Control of: 5-Nitrothiazol-2-amine

The invention discloses a chalcone thiazole amides, has the following general structure:, wherein R1 – R5 The respective independent is H, a halogen atom, C1 – C4 alkyl, C1 – C4 haloalkyl, nitro or C1 – C4 alkoxy. The chalcone thiazole amides to Clostridium difficile good inhibition effect, can be used for preventing Clostridium difficile infection or disease, in order to substitute the MTZ and the vancomycin. (by machine translation)

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Quality Control of: 5-Nitrothiazol-2-amine. In my other articles, you can also check out more blogs about 121-66-4

Reference：
Thiazole | C3H9421NS – PubChem,
Thiazole | chemical compound | Britannica

In an article, published in an article, once mentioned the application of 53266-94-7, Name is Ethyl 2-(2-aminothiazol-4-yl)acetate,molecular formula is C7H10N2O2S, is a conventional compound. this article was the specific content is as follows.Product Details of 53266-94-7

Compounds of the formula: STR1 wherein R1 is (C1 to C6) alkyl. R2 is carboxy or a protected carboxy group, R3 is amino or a protected amino group and A is hydroxyimino (C1 to C6) alkylene or (C1 to C6)-alkoxyimino (C1 to C6) alkylene, and pharmaceutically acceptable salt thereof, have been found to be active against various pathogenic microorganisms.

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Reference：
Thiazole | C3H10786NS – PubChem,
Thiazole | chemical compound | Britannica

Related Products of 348-40-3. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 348-40-3, Name is 6-Fluorobenzo[d]thiazol-2-amine

The imidazobenzothiazole compounds 3-17 together with the imidazobenzoxazole 18, and the imidazobenzoimidazole 19 were prepared and their cytotoxic activity evaluated at the National Cancer Institute (NCI) for testing against a panel of approximately 60 tumor cell lines. Compounds 5, 7, 8, and 16 exhibited interesting in vitro cytotoxic activity. The most active imidazobenzothiazole derivative 8 was further evaluated as a cytotoxic agent in the hollow fiber assay and showed a score greater than the minimum values for xenograft testing together with a net cell kill. Comparison with the results displayed in the in vivo assay by standard antitumor drugs in clinical use revealed a significant in vivo activity of the benzothiazole compound. COMPARE analyses for compounds 4-19 against the NCI’s standard agent database show poor or no correlation, and it might suggest for these compounds a mechanism of action unrelated to that of any known drug. Furthermore, the benzothiazole 8 did not show significant antitumor activity in a panel of two xenotransplanted tumors (i.e. colon and non-small cell lung tumors). By computing the polar surface area of compounds 3-19 with the MAREA computer program it was established that the most active compounds 5, 7, 8, and 16 should experience good intestinal permeability. Copyright

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Reference：
Thiazole | C3H10413NS – PubChem,
Thiazole | chemical compound | Britannica

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 348-40-3, Name is 6-Fluorobenzo[d]thiazol-2-amine, Product Details of 348-40-3.

A series of new pyrazolo-benzothiazole hybrids (7?26) were synthesised and screened for their cytotoxic activity towards several cancer cell lines [colon (HT-29), prostate (PC-3), lung (A549), glioblastoma (U87MG)] and normal human embryonic kidney cell line (Hek-293T). Compounds 8, 9, 13, 14, 18, 19, 23, and 24 displayed significant activity, with compound 14 being particularly potent towards all the tested cancer cell lines with IC50 values in the range 3.17?6.77 muM, even better than reference drug axitinib (4.88?21.7 muM). Compound 14 also showed the strongest growth inhibition in 3D multicellular spheroids of PC-3 and U87MG cells. The mechanism of cellular toxicity in PC-3 cells was found to be cell cycle arrest and apoptosis induction through depolarisation of mitochondrial membrane potential, increased ROS production and subsequent DNA damage. Further, compound 14 displayed significant in vitro (VEGFR-2 inhibition) and in vivo [transgenic zebrafish Tg(flila:EGFP) model] antiangiogenic properties. Overall, these results provide strong evidence that compound 14 could be considered for a lead candidate in anticancer and antiangiogenic drug discovery.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Product Details of 348-40-3. In my other articles, you can also check out more blogs about 348-40-3

Reference：
Thiazole | C3H10556NS – PubChem,
Thiazole | chemical compound | Britannica

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 4175-77-3, Name is 2,4-Dibromothiazole, Application In Synthesis of 2,4-Dibromothiazole.

A tetrazolinone compound represented by formula (1) [wherein Q represents a bivalent 5-membered aromatic heterocyclic group which may have at least one atom or group selected from the group P2; A represents a 5- to 10-membered monocyclic or condensed-cyclic heterocyclic group which may have at least one atom or group selected from the group P1; R1 and R2 independently represent a hydrogen atom or the like; R3 represents a C1-C6 alkyl group which may have at least one halogen atom or the like; R4, R5 and R6 independently represent a hydrogen atom or the like; and X represents an oxygen atom or a sulfur atom] has an excellent controlling effect on harmful organisms.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application In Synthesis of 2,4-Dibromothiazole. In my other articles, you can also check out more blogs about 4175-77-3

Reference：
Thiazole | C3H1423NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.137-00-8, Name is 4-Methyl-5-thiazoleethanol, molecular formula is C6H9NOS. In a Patent，once mentioned of 137-00-8, Recommanded Product: 4-Methyl-5-thiazoleethanol

Organic compounds having at least one ethylenically-unsaturated group are described, the organic compounds being suitable for use in coatable compositions as reactive diluents; compounds of the invention preferably have a divalent organic linking moiety devoid of reactive groups other than optional ethylenically-unsaturated groups, and a polar organic moiety and are particularly adept in solubilizing aminoplast resins having radiation-curable pendant groups.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Recommanded Product: 4-Methyl-5-thiazoleethanol, you can also check out more blogs about137-00-8

Reference：
Thiazole | C3H5457NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.80945-86-4, Name is 6-Bromo-2-chlorobenzothiazole, molecular formula is C7H3BrClNS. In a Patent，once mentioned of 80945-86-4, Computed Properties of C7H3BrClNS

Substituted imidazoles and thiazoles having the formula 1are useful for inhibiting farnesyltransferase. Also disclosed are farnesyltransferase-inhibiting compositions and methods of inhibiting farnesyltransferase in a patient.

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 80945-86-4 is helpful to your research., Computed Properties of C7H3BrClNS

Reference：
Thiazole | C3H10901NS – PubChem,
Thiazole | chemical compound | Britannica

Related Products of 5331-91-9, An article , which mentions 5331-91-9, molecular formula is C7H4ClNS2. The compound – 5-Chlorobenzo[d]thiazole-2(3H)-thione played an important role in people’s production and life.

Seven novel 3-(1-(2-(2,7a-dihydrobenzo[d]thiazol-2-ylthio)acetyl)-5- substituted-phenyl-4,5-dihydro-1H-pyrazol-3-yl)-2H-chromen-2-one derivatives were synthesized and characterized by 1H NMR and 13 C NMR. All of the compounds have been screened for their anticancer activity. The bioassay tests show that compound 4g exhibited potentially high activity against human gastric cancer cell SGC-7901 with IC50 value of 6.99±1.10 mug/mL. Docking simulation was performed to position compound 4g into the telomerase (3DU6) active site to determine the probable binding model.

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Reference：
Thiazole | C3H6300NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.4175-77-3, Name is 2,4-Dibromothiazole, molecular formula is C3HBr2NS. In a Patent，once mentioned of 4175-77-3, COA of Formula: C3HBr2NS

The present invention relates to novel Heterocycle-Substituted Tetracyclic Compounds of Formula (I): (I) and pharmaceutically acceptable salts thereof, wherein A, A’, R 2 R 3, R 4 and R are as defined herein. The present invention also relates to compositions comprising at least one Heterocycle-Substituted Tetracyclic Compound, and methods of using the Heterocycle-Substituted Tetracyclic Compounds for treating or preventing HCV infection in a patient.

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 4175-77-3 is helpful to your research., COA of Formula: C3HBr2NS

Reference：
Thiazole | C3H1272NS – PubChem,
Thiazole | chemical compound | Britannica