The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.137-00-8, Name is 4-Methyl-5-thiazoleethanol, molecular formula is C6H9NOS. In a Article，once mentioned of 137-00-8, name: 4-Methyl-5-thiazoleethanol
Commercial antibiotic therapies are becoming less efficient due to the emergence of bacterial resistance and the formation of bacterial biofilms. The design and development of novel antibacterial agents with efficient anti-biofilm/antibacterial activity and without bacterial resistance is becoming crucial. Herein, a series of poly(5-(2-ethyl acrylate)-4-methylthiazole-g-butyl) functionalized silver nanocomposites (PATA-C4@AgNPs) was synthesized, and their antimicrobial/anti-biofilm activity and biocompatibility were systematically evaluated. The multivalent cationic nanocomposites possessed strong antibacterial activity against both Gram-negative and Gram-positive bacteria without the emergence of bacterial resistance. The PATA-C4@AgNPs were found to disrupt the bacterial membrane and inhibit enzymatic activity. Importantly, these nanocomposites effectively eradicated over 60% of Staphylococcus aureus (S. aureus) and Pseudomonas aeruginosa (P. aeruginosa) biofilms at a low concentration of 16.7 mug mL-1. Furthermore, these nanocomposites showed selectivity for eliminating bacteria over human cells, thus avoiding cytotoxicity. The results demonstrated that these simple synthetic nanocomposites have great promise for applications in preventing bacterial infections.
The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 137-00-8 is helpful to your research., name: 4-Methyl-5-thiazoleethanol
Reference：
Thiazole | C3H5517NS – PubChem,
Thiazole | chemical compound | Britannica