A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 1123-93-9, Name is 1,3-Benzothiazol-5-amine, molecular formula is C7H6N2S. In a Patent,once mentioned of 1123-93-9, name: 1,3-Benzothiazol-5-amine
Proteolysis Targeting Chimeric molecules (Protacs) are bifunctional molecules which which can simultaneously bind a target protein and an E3 ubiquitin ligase thereby bringing the ligase and target in close proximity These bifunctional molecules allow the efficient ubiquitin transfer from the ligase complex to the target protein which is subsequently recognized by the proteasome and degraded. This degradation of the target protein provides treatment of diseases or conditions modulated through the target protein by effectively lowering the level of said target protein in the cells of the patient. The present invention provides Protac compounds incorporating a selective E3 Ligase IAP binding moiety (IAP binding moiety) as the degradation component, functioning to recruit target proteins to the E3 ubiquitin ligase IAP for degradation.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.name: 1,3-Benzothiazol-5-amine. In my other articles, you can also check out more blogs about 1123-93-9
Reference:
Thiazole | C3H294NS – PubChem,
Thiazole | chemical compound | Britannica