Synthetic Route of 2942-13-4. Let’s face it, organic chemistry can seem difficult to learn. Especially from a beginner’s point of view. Like 2942-13-4, Name is 6-Methoxybenzo[d]thiazole. In a document type is Article, introducing its new discovery.
Novel series of 3-amino-N-(4-aryl-1,1-dioxothian-4-yl)butanamides and 3-amino-N-(4-aryltetrahydropyran-4-yl)butanamides were synthesized and evaluated as dipeptidyl peptidase IV (DPP-IV) inhibitors. Derivatives incorporating the 6-substituted benzothiazole group showed highly potent DPP-IV inhibitory activity. Oral administration of (3R)-3-amino-4-(2,4,5-trifluorophenyl)-N-{4-[6-(2-methoxyethoxy)benzothiazol-2-yl]tetrahydropyran-4-yl}butanamide (12u) reduced blood glucose excursion in an oral glucose tolerance test.
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Reference:
Thiazole | C3H7172NS – PubChem,
Thiazole | chemical compound | Britannica