Electric Literature of 53218-26-1, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 53218-26-1, Name is 6-Bromobenzo[d]thiazole, molecular formula is C7H4BrNS. In a Article，once mentioned of 53218-26-1
The phosphoinositide 3-kinase (PI3K) family catalyzes the ATP-dependent phosphorylation of the 3?-hydroxyl group of phosphatidylinositols and plays an important role in cell growth and survival. There is abundant evidence demonstrating that PI3K signaling is dysregulated in many human cancers, suggesting that therapeutics targeting the PI3K pathway may have utility for the treatment of cancer. Our efforts to identify potent, efficacious, and orally available PI3K/mammalian target of rapamycin (mTOR) dual inhibitors resulted in the discovery of a series of substituted quinolines and quinoxalines derivatives. In this report, we describe the structure-activity relationships, selectivity, and pharmacokinetic data of this series and illustrate the in vivo pharmacodynamic and efficacy data for a representative compound.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 53218-26-1 is helpful to your research., Electric Literature of 53218-26-1
Reference：
Thiazole | C3H6886NS – PubChem,
Thiazole | chemical compound | Britannica