In an article, published in an article, once mentioned the application of 53137-27-2, Name is 2,4-Dimethylthiazole-5-carboxylic acid,molecular formula is C6H7NO2S, is a conventional compound. this article was the specific content is as follows.Application In Synthesis of 2,4-Dimethylthiazole-5-carboxylic acid
A facile ligand-free method for Pd(OAc)2 catalysed decarboxylative arylation of imidazo[1,2-a]pyridine-3-carboxylic acids with hetero(aryl) bromides has been developed. This method is applicable to a variety of (hetero)aryl bromides as coupling partners. Electron withdrawing and donating groups on imidazo[1,2-a]pyridine-3-carboxylic acids are well tolerated. It represents the first general protocol for ligand-free Pd(OAc)2 catalysed decarboxylative arylation of imidazo[1,2-a]pyridine-3-carboxylic acids with (hetero)aryl halides. A few of the compounds synthesized using this protocol showed antibacterial activity against Staphylococcus aureus.
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Reference:
Thiazole | C3H1693NS – PubChem,
Thiazole | chemical compound | Britannica