Final Thoughts on Chemistry for 2-Amino-4-chlorobenzothiazole

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Application of 19952-47-7, An article , which mentions 19952-47-7, molecular formula is C7H5ClN2S. The compound – 2-Amino-4-chlorobenzothiazole played an important role in people’s production and life.

Synthesis and ability to displace [3H]diazepam binding from rat brain membranes of the 3-(alkoxycarbonyl)-4H-pyrimido[2,1-b]benzothiazol-4-ones 3a-p and related compounds 10-12 are described. It has been found that some compounds bind to the benzodiazepine receptor (BZR) with potency greater than chlordiazepoxide. From a structure-affinity point of view the substitution at 6-position of pyrimido[2,1-b]benzothiazole nucleus was found conductive to higher affinity. In vitro data (GABA ratio) lend support to the fact that the most active compounds 3j, 1 might possess agonist properties at BZR.

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Reference:
Thiazole | C3H9991NS – PubChem,
Thiazole | chemical compound | Britannica