New explortion of Ethyl 2-(2-aminothiazol-4-yl)-2-oxoacetate

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 64987-08-2 is helpful to your research., Product Details of 64987-08-2

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.64987-08-2, Name is Ethyl 2-(2-aminothiazol-4-yl)-2-oxoacetate, molecular formula is C7H8N2O3S. In a Article,once mentioned of 64987-08-2, Product Details of 64987-08-2

A series of monobactam derivatives were prepared and evaluated for their antibacterial activities against susceptible and resistant Gram-negative strains, taking Aztreonam and BAL30072 as the leads. Six conjugates (12a-f) bearing PIH-like siderophore moieties were created to enhance the bactericidal activities against Gram-negative bacteria based on Trojan Horse strategy, and all of them displayed potencies against susceptible Gram-negative strains with MIC ? 8 mug/mL. SAR revealed that the polar substituents on the oxime side chain were beneficial for activities against resistant Gram-negative bacteria. Compounds 19c and 33a-b exhibited the promising potencies against ESBLs-producing E. coli and Klebsiella pneumoniae with MICs ranging from 2 mug/mL to 8 mug/mL. These results offered powerful information for further strategic optimization in search of the antibacterial candidates against MDR Gram-negative bacteria.

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 64987-08-2 is helpful to your research., Product Details of 64987-08-2

Reference:
Thiazole | C3H7748NS – PubChem,
Thiazole | chemical compound | Britannica