A new application about 6-Bromobenzo[d]thiazole

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.SDS of cas: 53218-26-1. In my other articles, you can also check out more blogs about 53218-26-1

53218-26-1, Name is 6-Bromobenzo[d]thiazole, molecular formula is C7H4BrNS, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 53218-26-1, SDS of cas: 53218-26-1

Primary arylamines are an important unit broadly found in synthetic, biological, and materials science. Herein we describe the development of a (NHC)Cu system that mediates a direct C-H amidation of (hetero)arenes by using N-chlorocarbamates or their sodio derivatives as the practical amino sources. A facile stoichiometric reaction of reactive copper-aryl intermediates with the amidating reagent led us to isolate key copper arylcarbamate species with the formation of a C-N bond. The use of tBuONa base made this transformation catalytic under mild conditions. The present (NHC)Cu-catalyzed C-H amidation works efficiently and selectively on a large scale over a range of arenes including polyfluorobenzenes, azoles, and quinoline N-oxides. Deprotection of the newly installed carbamate groups such as Boc and Cbz was readily performed to afford the corresponding primary arylamines.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.SDS of cas: 53218-26-1. In my other articles, you can also check out more blogs about 53218-26-1

Reference：
Thiazole | C3H6902NS – PubChem,
Thiazole | chemical compound | Britannica