39736-29-3, Name is Ethyl 4-amino-2-(methylthio)thiazole-5-carboxylate, molecular formula is C7H10N2O2S2, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 39736-29-3, name: Ethyl 4-amino-2-(methylthio)thiazole-5-carboxylate
The invention belongs to the technical field of pharmaceutical intermediates, relates to a 4 – amino-thiazole – 5 – carboxylic acid ethyl ester synthesis method, steps which consists in: the 4 – amino – 2 – (methylthio) thiazole – 5 – carboxylic acid ethyl ester dissolved in ethanol, adding concentrated hydrochloric acid, adding zinc powder batches under stirring, reflux reaction for 4 hours, to obtain the neutralizing liquid; to the neutralizing liquid is filtered, the filter cake washing with ethanol for 2 – 3 times, the filtrate concentrated under reduced pressure, to obtain the concentrated solution; adding the concentrated in methylene chloride and water, stirring, separating the organic phase; the organic phase with saturated sodium chloride solution for washing, drying with anhydrous sodium sulfate, concentrated, isopropyl alcohol recrystallize to get 4 – amino thiazole – 5 – carboxylic acid ethyl ester. The invention also provides a method for removing from a thio group on the aromatic ring of the new method, the raw materials are low cost, high yield, and suitable for production. (by machine translation)
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.name: Ethyl 4-amino-2-(methylthio)thiazole-5-carboxylate. In my other articles, you can also check out more blogs about 39736-29-3
Reference：
Thiazole | C3H8229NS – PubChem,
Thiazole | chemical compound | Britannica