A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 2103-99-3, Name is 4-(4-Chlorophenyl)thiazol-2-amine, molecular formula is C9H7ClN2S. In a Article，once mentioned of 2103-99-3, Recommanded Product: 4-(4-Chlorophenyl)thiazol-2-amine
A series of imidazo[2,1-b]thiazoles bearing pyrazole moieties 4-6(a-c) was synthesized through the reaction of 6-hydrazinylimidazo[2,1-b]thiazoles 3a-c with different beta-dicarbonyl compounds. Eleven compounds were screened at the National Cancer Institute (NCI), USA for anticancer activity at a single dose (10 muM). The in vitro anticancer evaluation revealed that compounds 2a and 4-6(a) exhibited increased potency towards CNS SNB-75 and Renal UO-31 cancer cell lines. COMPARE analyses showed strong to considerable correlations with rapamycin (mTOR inhibitor). The results of assessment of toxicities, druglikeness, and drug score profiles of compounds 2a and 4-6(a) are promising. Some of the target compounds showed good docking scores with potential anticancer targets, chosen based on pharmacophore mapping of the established derivatives.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.Recommanded Product: 4-(4-Chlorophenyl)thiazol-2-amine, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 2103-99-3, in my other articles.
Reference：
Thiazole | C3H10282NS – PubChem,
Thiazole | chemical compound | Britannica