Synthetic Route of 3364-80-5, Chemistry can be defined as the study of matter and the changes it undergoes. You’ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology.3364-80-5, Name is Thiazole-4-carboxaldehyde, molecular formula is C4H3NOS. In a patent, introducing its new discovery.
The addition of the SuperQuat enolate to five- and six-membered heterocyclic tert-butyl sulfinimines led to a high syn-selectivity of up to 99:1 in good to excellent yields. The reaction is tentatively proposed to proceed through an open-chain transition state with the presence of an alpha-heteroatom on the sulfinimine leading to high diastereoselectivities. The adducts were derivatized to beta-amino esters and amides in a facile manner.
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Reference：
Thiazole | C3H9291NS – PubChem,
Thiazole | chemical compound | Britannica