14-Sep-2021 News Discovery of 4-(Thiazol-2-yl)aniline

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Application of 193017-26-4, An article , which mentions 193017-26-4, molecular formula is C9H8N2S. The compound – 4-(Thiazol-2-yl)aniline played an important role in people’s production and life.

Spiroannulation of ketals derived from unsaturated cyclohexenone derivatives by the Lewis acid-catalyzed reaction of l,2-bis((trimethylsilyl)oxy)cyclobutene 5 led to spiro[4.5]decene-diones 9 and 30. These were transformed into spiro[4.4]nonene derivatives 25 and 35/36 via similar sequences involving ozonolysis and aldol ring reclosure. Reduction of an annular double bond allowed facile closure of a third ring, also by an aldol reaction. This work led to a single oxygenated angular triquinane 28 from 9, and to the tricyclo[6.2.1.01,5]undecane derivative 41 from 30. An oxatricyclo[5.3.1.01,5]undecane derivative 19 was also obtained from 9.

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Reference:
Thiazole | C3H4844NS – PubChem,
Thiazole | chemical compound | Britannica