With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.14779-17-0,2-Amino-5-methylbenzothiazole,as a common compound, the synthetic route is as follows.
General procedure: To a 10 mL round bottom flask was added 0.5 mmolof the amine and 0.1 mL of acetic anhydride. The reactionis instantaneous and exothermic, and after 10 s the solidproduct formed was filtered and washed with cold water.When no solid was immediately formed, 4 mL of coldwater was added, and the mixture allowed standing ina refrigerator for 24 h, leading to precipitation. To allsynthesized acetamides, measured physical data were inagreement to the reported values.17-19,27,31,32
14779-17-0, As the paragraph descriping shows that 14779-17-0 is playing an increasingly important role.
Reference:
Article; Cunha, Silvio; De Santana, Lourenco L. B.; Journal of the Brazilian Chemical Society; vol. 28; 6; (2017); p. 1137 – 1144;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica